The Arizona Diamondbacks visit the Colorado Rockies on Wednesday, September 23, 2026. Arizona holds a solid record at 83-74, while Colorado struggles with a 57-100 mark. This gap in performance is reflected in the betting odds.
Arizona is favored with a moneyline of -162, meaning you’d need to bet $162 to win $100 on them outright. Colorado’s underdog price is +134, offering a bigger payout if they pull off a surprise win. The spread is set at 1.5 runs, with Arizona as the favorite at -1.5 (-107). This means Arizona must win by at least two runs for a spread bet on them to pay off. The Rockies get +1.5 runs at -112, so a loss by one run or a win results in a winning bet on Colorado’s side.
The total runs line is at 11.0, with the over priced at -115 and the under at -105. This suggests bookmakers expect a moderately high-scoring game. The slight edge on the under indicates a close call between betting on a game with more than 11 runs or fewer.
Given Arizona’s stronger record and favored odds, they look like the safer pick. However, the spread requires a two-run margin, so consider if Arizona can win comfortably. The total is high, so unless you expect a pitching duel, the over might be worth a look.
In summary, Arizona is favored but must cover the 1.5-run spread, while the total line hints at a lively game with scoring opportunities on both sides.