Colorado Buffaloes vs Oklahoma State Cowboys

Saturday, October 24, 2026 7:00 PM ET Game 17081222
Colorado Buffaloes
Away
Colorado Buffaloes
VS
Home
Oklahoma State Cowboys
Oklahoma State Cowboys
Game Analysis

This Saturday’s matchup features the Colorado Buffaloes visiting the Oklahoma State Cowboys. The Buffaloes come in at 2-4, while the Cowboys have a more solid 4-2 record. That difference in performance is reflected in the betting lines.

Oklahoma State is favored by 13.5 points. The home spread at -13.5 with -112 odds means the Cowboys need to win by at least 14 points for spread bettors to cash a ticket. Meanwhile, Colorado is the underdog with the +13.5 spread at -108 odds. If you think the Buffaloes can keep the game closer than two touchdowns or even pull an upset, the underdog spread is your play.

Looking at moneylines, Oklahoma State is a heavy favorite at -550, meaning you’d have to bet $550 to win $100. Colorado’s moneyline sits at a hefty +410, offering a big payout if the Buffaloes pull off the upset. This reflects the market’s confidence in Oklahoma State’s ability to win comfortably.

The total points line is set at 56.5. The odds are nearly even for over (-108) and under (-112), indicating an expectation of a moderately high-scoring game. If you believe both offenses will put up points, the over is worth considering, but the close odds suggest a balanced contest in scoring.

In summary, the market favors Oklahoma State to win big. Betting the spread or moneyline on the Cowboys aligns with the records and odds. However, if you expect Colorado to keep it close, the underdog spread or moneyline offers value. The total points line suggests an exciting, moderately high-scoring game.

Analysis updated October 24, 2026 at 7:02 AM
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