The Philadelphia Flyers visit the Buffalo Sabres on Wednesday, October 21, 2026. The Flyers come in with a 2-6 record, struggling early in the season. Meanwhile, the Sabres hold a better mark at 4-3, showing more consistency.
Looking at the betting odds, Buffalo is favored at home with a moneyline of -185. This means a bettor would need to wager $185 to win $100 on the Sabres outright. Philadelphia’s moneyline is +154, so a $100 bet on the Flyers would pay $154 if they pull off the upset.
The spread is set at 1.5 goals. Buffalo is -1.5 at +136, meaning you’d win $136 on a $100 bet if Buffalo wins by two or more goals. Philadelphia is +1.5 at -162, so you’d need to bet $162 to win $100 on the Flyers keeping the game within one goal or winning.
The over/under total is 5.5 goals. The over is priced at -135, meaning a $135 bet is needed to win $100 if the combined score is six or more. The under is +114, so a $100 wager pays $114 if the total goals are five or fewer.
Given Buffalo’s better record and home favorite status, backing the Sabres on the moneyline or spread looks reasonable. However, the Flyers’ underdog price is tempting if you expect a tight game. The total suggests a moderately high-scoring affair, but the under offers decent value if you expect defenses to hold strong.