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San Francisco 49ers vs Los Angeles Rams 9/22/24 NFL Free Pick

This weekend, the San Francisco 49ers will be facing off against the Los Angeles Rams in what is sure to be an exciting matchup between these two top teams in the NFL. The 49ers, with a 1-1 record for the season, will be looking to bounce back after a tough loss in their last game. On the other hand, the Rams, with a 0-2 record, will be playing at home where they have a 1-0 record so far this season.

Both teams have shown flashes of excellence so far this season, but will be hungry for a win in this upcoming game. With the 49ers determined to improve their road record and the Rams looking to turn around their recent losses, Sunday's game is sure to be a hard-fought battle between two talented teams. Fans can expect to see a thrilling display of athleticism and skill as these two teams go head to head in Los Angeles.

Our simulated predicted game score is Los Angeles Rams 26 and San Francisco 49ers 19.

THE PICK: San Francisco 49ers
THE BET: -7 -115

San Francisco vs Los Angeles Betting Odds

Spread, Total, Moneyline. It's important to note that betting odds can change leading up to the game, so be sure to check for updates.

TeamSpreadMLTotal
San Francisco-7
-115
-350o44.5
-115
Los Angeles+7
-105
+275u44.5
-115