PIT

NYY

---

Pittsburgh Pirates vs New York Yankees 9/21/22 MLB Free Pick

Our simulated predicted game score is Pittsburgh Pirates 5 and New York Yankees 3.

Matt Moorhead

THE PICK: New York Yankees
THE BET: -300

Jay Marriucci

THE PICK: New York Yankees
THE BET: -300

Jimmy Doyle

THE PICK: New York Yankees
THE BET: -300

Zhou Wei

THE PICK: New York Yankees
THE BET: -300

Lou Barry

THE PICK: New York Yankees
THE BET: -300

Pittsburgh vs New York Betting Odds

Spread, Total, Moneyline. It's important to note that betting odds can change leading up to the game, so be sure to check for updates.