NYG

SF

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New York Giants vs San Francisco 49ers 9/21/23 NFL Free Pick

Our simulated predicted game score is New York Giants 27 and San Francisco 49ers 16.

Aaron Kelly

THE PICK: San Francisco 49ers
THE BET: -10 -110

Doc Holliday

THE PICK: San Francisco 49ers
THE BET: -10 -110

Leonard Bryant

THE PICK: San Francisco 49ers
THE BET: -10 -110

Eduardo Costa Verez

THE PICK: San Francisco 49ers
THE BET: -10 -110

The Public Enemy

THE PICK: San Francisco 49ers
THE BET: -10 -110

Jimmy McGuire

THE PICK: San Francisco 49ers
THE BET: -10 -110

Ben Obama

THE PICK: San Francisco 49ers
THE BET: -10 -110

George Smeader

THE PICK: San Francisco 49ers
THE BET: -10 -110

Joe Gunn

THE PICK: San Francisco 49ers
THE BET: -10 -110

High Rollers Club

THE PICK: San Francisco 49ers
THE BET: -10 -110

Sports-Pick

THE PICK: San Francisco 49ers
THE BET: -10 -110

Jimmy Doyle

THE PICK: San Francisco 49ers
THE BET: -10 -110

New York vs San Francisco Betting Odds

Spread, Total, Moneyline. It's important to note that betting odds can change leading up to the game, so be sure to check for updates.